Combining Isotopic Tracer Techniques to Increase Efficiency of Clinical Pharmacokinetic Trials in Oncology

Ethical guideposts to clinical trials in oncology

Clinical research with human subjects is an ethically challenging task requiring ultimate trust on the part of patients and ultimate respect for persons on the part of clinical researchers. The author provides a simple framework to help researchers ensure the ethical integrity of a clinical trial in oncology.

Clinical Trials in Paediatric Oncology

Childhood and adolescent cancers are rare diseases. Despite the progress in treatment (more than two-thirds of all cases are cured), cancer remains the leading cause of death by disease in children older than 1 year. Access to new drugs that are more efficacious or better tolerated is therefore an important public health priority. The objective of our round table was thus to take inventory of t...

Combining Parallelization Techniques to Increase Adaptability and Efficiency of Multiprocessing Dsp Systems

Current digital signal processing (DSP) applications are requiring processing-performance metrics on the order of Tereflops (10 floating point operations per second). The announcements of RISC processors capable of performing billions of floating point operations per second and nearly an order of magnitude better on integer arithmetic address this need. Additionally, interconnect fabrics that s...

Combining Financial Management and Collections to Increase Revenue and Efficiency

Clinical Trials in Oncology and Defining Benefit

In the editorial “The Evolution of Clinical Trials in Oncology: Defining Who Benefits from New Drugs Using Innovative Study Designs” [1], Goldberg et al. nicely discuss many changing aspects of clinical trial design in oncology. However, I believe their title is misleading. No study will define “who benefits” but only who might benefit. For example, human epidermal growth receptor 2 overexpress...